Biomedical Polymers Laboratory

Biomolecular simulation and computational chemistry; therapeutic design and delivery

See my WWW page at http://www.chpc.utah.edu/~cheatham and the lab pages at http://amber.chpc.utah.edu.

We use advanced simulation methods on computers to understand biomolecular structure, function, dynamics and interaction. Example studies include the simulation of pH-sensitive peptide "accuators" embedded in polymeric micelles (in collaboration with YH Bae), design of coiled-coil structures (in collaboration with YB Yu), development of wavelet transformations to smooth simulation data (in collaboration with J Facelli), simulation of large protein assemblies including the proteasome (in collaboration with Chris Hill), and other projects...

For a full list of publications, see http://www.chpc.utah.edu/~cheatham/publications.html

Cheatham TE 3r , Simulation and modeling of nucleic acid structure, dynamics and interactions. Curr Opin Struct Biol 2004 Jun;14(3):360-7

Cheatham TE 3rd, Young M , Molecular dynamics simulation of nucleic acids: successes, limitations, and promise. Biopolymers 2000-2001;56(4):232-56

Cheatham TE 3rd, Kollman P , Molecular dynamics simulation of nucleic acids. Annu Rev Phys Chem 2000;51():435-71