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Alexey V Zaitsev

Alexey V Zaitsev

Research Associate Professor
Research Associate Professor

E-mail:

http://www.cvrti.utah.edu/personnel/zaitsev/zaitsev.html

Phone: 801-587-5834
Office: CVRTI Rm 235<

Lab

Cardiovascular Research and Training Institute

Research

Mechanisms of cardiac arrhythmias; myocardial ischemia; real-time physiological imaging of single cardiac myocytes and whole hearts

Current Research

The current focus of Dr. Zaitsev's group is the mechanisms of ventricular fibrillation in normal and ischemic hearts.

Active Grants
PI “Ventricular Fibrillation in a Globally Ischemic Heart: From Cell to ECG” (NIH R01 HL088444-01A1)
PI "Mechanisms of Asystole and Contractile Dysfunction in an Experimental Model of Sudden Cardiac Arrest" (Nora Eccles Treadwell Foundation Research Grant)

Selected Publications

Wasmund SL, Pai RK, Freedman RA, Abedin M, Daccarett M, Segerson NM, Zaitsev AV, Hamdan MH, Modulation of the sinus rate during ventricular fibrillation. J Cardiovasc Electrophysiol 2009 Feb;20(2):187-92

Shvedko AG, Warren MD, Shome S, Stinstra J, Zaitsev AV, Influence of the skeletal muscle activity on time and frequency domain properties of the body surface ECG during evolving ventricular fibrillation in the pig. Resuscitation 2008 Aug;78(2):215-23

Matiukas A, Mitrea BG, Qin M, Pertsov AM, Shvedko AG, Warren MD, Zaitsev AV, Wuskell JP, Wei MD, Watras J, Loew LM, Near-infrared voltage-sensitive fluorescent dyes optimized for optical mapping in blood-perfused myocardium. Heart Rhythm 2007 Nov;4(11):1441-51

Warren M, Huizar JF, Shvedko AG, Zaitsev AV, Spatiotemporal relationship between intracellular Ca2+ dynamics and wave fragmentation during ventricular fibrillation in isolated blood-perfused pig hearts. Circ Res 2007 Oct 26;101(9):e90-101

Tanaka K, Zlochiver S, Vikstrom KL, Yamazaki M, Moreno J, Klos M, Zaitsev AV, Vaidyanathan R, Auerbach DS, Landas S, Guiraudon G, Jalife J, Berenfeld O, Kalifa J, Spatial distribution of fibrosis governs fibrillation wave dynamics in the posterior left atrium during heart failure. Circ Res 2007 Oct 12;101(8):839-47

Huizar JF, Warren MD, Shvedko AG, Kalifa J, Moreno J, Mironov S, Jalife J, Zaitsev A , Three distinct phases of VF during global ischemia in the isolated blood-perfused pig heart. Am J Physiol Heart Circ Physiol 2007 Sep;293(3):H1617-28