Selected Publications

Kim D, Gao ZG, Lee ES, Bae YH, In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer. Mol Pharm 2009 Sep-Oct;6(5):1353-62

Kang SW, Bae YH, Cryopreservable and tumorigenic three-dimensional tumor culture in porous poly(lactic-co-glycolic acid) microsphere. Biomaterials 2009 Sep;30(25):4227-32

Park K, Bae YH, Grainger DW, The 14th International Symposium on Recent Advances in Drug Delivery Systems, February 15-18, 2009, Salt Lake City, UT, USA. J Control Release 2009 Sep 12;():

Kang HC, Bae YH, Transfection of rat pancreatic islet tissue by polymeric gene vectors. Diabetes Technol Ther 2009 Jul;11(7):443-9

Kang HC, Bae YH, Transfection of insulin-secreting cell line and rat islets by functional polymeric gene vector. Biomaterials 2009 May;30(14):2837-45

Yin H, Bae YH, Physicochemical aspects of doxorubicin-loaded pH-sensitive polymeric micelle formulations from a mixture of poly(L-histidine)-b-poly(L-lactide)-b-poly(ethylene glycol). Eur J Pharm Biopharm 2009 Feb;71(2):223-30

Bae YH, Drug targeting and tumor heterogeneity. J Control Release 2009 Jan 5;133(1):2-3

Lee ES, Gao Z, Bae YH, Recent progress in tumor pH targeting nanotechnology. J Control Release 2008 Dec 18;132(3):164-70

Kim D, Lee ES, Oh KT, Gao ZG, Bae YH, Doxorubicin-loaded polymeric micelle overcomes multidrug resistance of cancer by double-targeting folate receptor and early endosomal pH. Small 2008 Nov;4(11):2043-50

Bae YH, Yin H, Stability issues of polymeric micelles. J Control Release 2008 Oct 6;131(1):2-4

Kim D, Lee ES, Park K, Kwon IC, Bae YH, Doxorubicin loaded pH-sensitive micelle: antitumoral efficacy against ovarian A2780/DOXR tumor. Pharm Res 2008 Sep;25(9):2074-82

Lee ES, Gao Z, Kim D, Park K, Kwon IC, Bae YH, Super pH-sensitive multifunctional polymeric micelle for tumor pH(e) specific TAT exposure and multidrug resistance. J Control Release 2008 Aug 7;129(3):228-36

Taluja A, Bae YH, Role of a novel multifunctional excipient poly(ethylene glycol)-block-oligo(vinyl sulfadimethoxine) in controlled release of lysozyme from PLGA microspheres. Int J Pharm 2008 Jun 24;358(1-2):50-9

Oh KT, Lee ES, Kim D, Bae YH, L-histidine-based pH-sensitive anticancer drug carrier micelle: reconstitution and brief evaluation of its systemic toxicity. Int J Pharm 2008 Jun 24;358(1-2):177-83

Yin H, Lee ES, Kim D, Lee KH, Oh KT, Bae YH, Physicochemical characteristics of pH-sensitive poly(L-histidine)-b-poly(ethylene glycol)/poly(L-lactide)-b-poly(ethylene glycol) mixed micelles. J Control Release 2008 Mar 3;126(2):130-8

Sethuraman VA, Lee MC, Bae YH, A biodegradable pH-sensitive micelle system for targeting acidic solid tumors. Pharm Res 2008 Mar;25(3):657-66

Lee ES, Oh KT, Kim D, Youn YS, Bae YH, Tumor pH-responsive flower-like micelles of poly(L-lactic acid)-b-poly(ethylene glycol)-b-poly(L-histidine). J Control Release 2007 Oct 18;123(1):19-26

Qiu LY, Bae YH, Self-assembled polyethylenimine-graft-poly(epsilon-caprolactone) micelles as potential dual carriers of genes and anticancer drugs. Biomaterials 2007 Oct;28(28):4132-42

Mohajer G, Lee ES, Bae YH, Enhanced intercellular retention activity of novel pH-sensitive polymeric micelles in wild and multidrug resistant MCF-7 cells. Pharm Res 2007 Sep;24(9):1618-27

Taluja A, Bae YH, Role of a novel excipient poly(ethylene glycol)-b-poly(L-histidine) in retention of physical stability of insulin at aqueous/organic interface. Mol Pharm 2007 Jul-Aug;4(4):561-70

Taluja A, Bae YH, Role of a novel excipient poly(ethylene glycol)-b-poly(L-histidine) in retention of physical stability of insulin in aqueous solutions. Pharm Res 2007 Aug;24(8):1517-26

Sethuraman VA, Bae YH, TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors. J Control Release 2007 Apr 2;118(2):216-24

Kang HC, Bae YH, Polymeric gene transfection on insulin-secreting cells: sulfonylurea receptor-mediation and transfection medium effect. Pharm Res 2006 Aug;23(8):1797-808

Zhu W, Masaki T, Bae YH, Rathi R, Cheung AK, Kern SE, Development of a sustained-release system for perivascular delivery of dipyridamole. J Biomed Mater Res B Appl Biomater 2006 Apr;77(1):135-43

Qiu LY, Bae YH, Polymer architecture and drug delivery. Pharm Res 2006 Jan;23(1):1-30

Sethuraman VA, Na K, Bae YH, pH-responsive sulfonamide/PEI system for tumor specific gene delivery: an in vitro study. Biomacromolecules 2006 Jan;7(1):64-70

Gao ZG, Lee DH, Kim DI, Bae YH, Doxorubicin loaded pH-sensitive micelle targeting acidic extracellular pH of human ovarian A2780 tumor in mice. J Drug Target 2005 Aug;13(7):391-7

Kang HC, Kim S, Lee M, Bae YH, Polymeric gene carrier for insulin secreting cells: poly(L-lysine)-g-sulfonylurea for receptor mediated transfection. J Control Release 2005 Jun 20;105(1-2):164-76

Kim S, Wan Kim S, Bae YH, Synthesis, bioactivity and specificity of glucagon-like peptide-1 (7-37)/polymer conjugate to isolated rat islets. Biomaterials 2005 Jun;26(17):3597-606

Lee ES, Na K, Bae YH, Doxorubicin loaded pH-sensitive polymeric micelles for reversal of resistant MCF-7 tumor. J Control Release 2005 Mar 21;103(2):405-18

Lee ES, Na K, Bae YH, Super pH-sensitive multifunctional polymeric micelle. Nano Lett 2005 Feb;5(2):325-9

Kim S, Bae YH, Long-term insulinotropic activity of glucagon-like peptide-1/polymer conjugate on islet microcapsules. Tissue Eng 2004 Nov-Dec;10(11-12):1607-16

Kang HC, Lee M, Bae YH, Polymeric gene carriers. Crit Rev Eukaryot Gene Expr 2005;15(4):317-42

Chae SY, Kim YY, Kim SW, Bae YH, Prolonged glucose normalization of streptozotocin-induced diabetic mice by transplantation of rat islets coencapsulated with crosslinked hemoglobin. Transplantation 2004 Aug 15;78(3):392-7

Na K, Lee KH, Bae YH, pH-sensitivity and pH-dependent interior structural change of self-assembled hydrogel nanoparticles of pullulan acetate/oligo-sulfonamide conjugate. J Control Release 2004 Jul 7;97(3):513-25

Bae YH, Caged pancreatic islet for IDDM. Yonsei Med J 2004 Jun 30;45 Suppl():56-60

Kim S, Bae YH, Visual evidence and quantification of interaction of polymeric sulfonylurea with pancreatic islet. Biomacromolecules 2003 Nov-Dec;4(6):1550-7

Lee ES, Na K, Bae YH, Polymeric micelle for tumor pH and folate-mediated targeting. J Control Release 2003 Aug 28;91(1-2):103-13

Lee ES, Shin HJ, Na K, Bae YH, Poly(L-histidine)-PEG block copolymer micelles and pH-induced destabilization. J Control Release 2003 Jul 31;90(3):363-74

Na K, Lee ES, Bae YH, Adriamycin loaded pullulan acetate/sulfonamide conjugate nanoparticles responding to tumor pH: pH-dependent cell interaction, internalization and cytotoxicity in vitro. J Control Release 2003 Feb 21;87(1-3):3-13

Ahn CH, Chae SY, Bae YH, Kim SW, Biodegradable poly(ethylenimine) for plasmid DNA delivery. J Control Release 2002 Apr 23;80(1-3):273-82

Gappa H, Baudys M, Koh JJ, Kim SW, Bae YH, The effect of zinc-crystallized glucagon-like peptide-1 on insulin secretion of macroencapsulated pancreatic islets. Tissue Eng 2001 Feb;7(1):35-44

Chae SY, Kim SW, Bae YH, Bioactive polymers for biohybrid artificial pancreas. J Drug Target 2001;9(6):473-84

Vernon B, Kim SW, Bae YH, Thermoreversible copolymer gels for extracellular matrix. J Biomed Mater Res 2000 Jul;51(1):69-79

Jeong B, Bae YH, Kim SW, In situ gelation of PEG-PLGA-PEG triblock copolymer aqueous solutions and degradation thereof. J Biomed Mater Res 2000 May;50(2):171-7

Jeong B, Bae YH, Kim SW, Drug release from biodegradable injectable thermosensitive hydrogel of PEG-PLGA-PEG triblock copolymers. J Control Release 2000 Jan 3;63(1-2):155-63

Jeong B, Choi YK, Bae YH, Zentner G, Kim SW, New biodegradable polymers for injectable drug delivery systems. J Control Release 1999 Nov 1;62(1-2):109-14

Vernon B, Kim SW, Bae YH, Insulin release from islets of Langerhans entrapped in a poly(N-isopropylacrylamide-co-acrylic acid) polymer gel. J Biomater Sci Polym Ed 1999;10(2):183-98

Jeong B, Bae YH, Lee DS, Kim SW, Biodegradable block copolymers as injectable drug-delivery systems. Nature 1997 Aug 28;388(6645):860-2

Gutowska A, Bae YH, Jacobs H, Mohammad F, Mix D, Feijen J, Kim SW, Heparin release from thermosensitive polymer coatings: in vivo studies. J Biomed Mater Res 1995 Jul;29(7):811-21

Yang Y, Jacobs H, Bae YH, Kim SW, Selective protein transport through a thin cellulose coated porous membrane. Biotechnol Bioeng 1994 Feb 5;43(3):207-14

Pai CM, Jacobs H, Bae YH, Kim SW, Synthesis and characterization of soluble concanavalin A oligomer. Biotechnol Bioeng 1993 Apr 25;41(10):957-63

Pai CM, Bae YH, Mack EJ, Wilson DE, Kim SW, Concanavalin A microspheres for a self-regulating insulin delivery system. J Pharm Sci 1992 Jun;81(6):532-6

Kim SW, Bae YH, Okano T, Hydrogels: swelling, drug loading, and release. Pharm Res 1992 Mar;9(3):283-90

Kwon IC, Bae YH, Kim SW, Electrically erodible polymer gel for controlled release of drugs. Nature 1991 Nov 28;354(6351):291-3

Bae YH, Okano T, Kim SW, "On-off" thermocontrol of solute transport. II. Solute release from thermosensitive hydrogels. Pharm Res 1991 May;8(5):624-8

Bae YH, Okano T, Kim SW, "On-off" thermocontrol of solute transport. I. Temperature dependence of swelling of N-isopropylacrylamide networks modified with hydrophobic components in water. Pharm Res 1991 Apr;8(4):531-7