Selected Publications

Luo W, Gangwal K, Sankar S, Boucher KM, Thomas D, Lessnick SL, GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance. Oncogene 2009 Aug 31;():

Gangwal K, Lessnick SL, Microsatellites are EWS/FLI response elements: genomic "junk" is EWS/FLI's treasure. Cell Cycle 2008 Oct;7(20):3127-32

Gangwal K, Sankar S, Hollenhorst PC, Kinsey M, Haroldsen SC, Shah AA, Boucher KM, Watkins WS, Jorde LB, Graves BJ, Lessnick SL, Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Proc Natl Acad Sci U S A 2008 Jul 22;105(29):10149-54

Hancock JD, Lessnick SL, A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature. Cell Cycle 2008 Jan 15;7(2):250-6

Owen LA, Kowalewski AA, Lessnick SL, EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma. PLoS One 2008 Apr 16;3(4):e1965

Haldar M, Hancock JD, Coffin CM, Lessnick SL, Capecchi MR, A conditional mouse model of synovial sarcoma: insights into a myogenic origin. Cancer Cell 2007 Apr;11(4):375-88

Braunreiter CL, Hancock JD, Coffin CM, Boucher KM, Lessnick SL, Expression of EWS-ETS fusions in NIH3T3 cells reveals significant differences to Ewing's sarcoma. Cell Cycle 2006 Dec;5(23):2753-9

Kinsey M, Smith R, Lessnick SL, NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma. Mol Cancer Res 2006 Nov;4(11):851-9

Owen LA, Lessnick SL, Identification of target genes in their native cellular context: an analysis of EWS/FLI in Ewing's sarcoma. Cell Cycle 2006 Sep;5(18):2049-53

Smith R, Owen LA, Trem DJ, Wong JS, Whangbo JS, Golub TR, Lessnick SL, Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma. Cancer Cell 2006 May;9(5):405-16