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Yan-Ting (Elizabeth) Shiu

Yan-Ting (Elizabeth) Shiu

Assistant Professor
Advisor, BS/MS Program
1990-1994, B.S., Chemical Engineering, National Taiwan University
1994-1999, Ph.D., Chemical Engineering, Rice University
1999-2001, Postgraduate Researcher, Bioengineering, University of California-San Diego

E-mail:

http://www.bioen.utah.edu/faculty/Yts/ResearchMain.htm

Phone: 801-581-3615
Phone: Lab 801-585-0677
Phone: Fax 801-585-5361
Office: 2474 MEB<

Lab

Vascular Bioengineering Laboratory

Research

Vascular Devices, Vascular Cell and Tissue Engineering, Computational and Experimental Biotransport Phenomena, Biomechanics, Hematology

Current Research

Primary research interests:
- Devices: stents, synthetic vascular grafts, implanted drug delivery devices
- Transport phenomena in blood vessels and perivascular tissues (related to drug delivery)
- Bioengineering aspects of vascular assembly, repair, and pathophysiology
- Vascular complications in type I and type II diabetes
- Medical imaging for visualization of blood flow and vessel walls

Recent book chapters:
- Shiu YT. Mechanical forces on cells. In: Bronzino JD, ed. Tissue Engineering and Artificial Organs/The Biomedical Engineering Handbook (3rd edition). Boca Raton: CRC Press; 2006:33.1-33.18.
- Shiu YT. Mechanical forces on cells. In: Fisher JP, Mikos AG, Bronzino JD, eds. Tissue engineering (1st edition). Boca Raton: CRC Press; 2007:4.1-4.18.

Selected Publications

Li L, Terry CM, Shiu YT, Cheung AK, Neointimal hyperplasia associated with synthetic hemodialysis grafts. Kidney Int 2008 Nov;74(10):1247-61

Joung IS, Iwamoto MN, Shiu YT, Quam CT, Cyclic strain modulates tubulogenesis of endothelial cells in a 3D tissue culture model. Microvasc Res 2006 Jan;71(1):1-11

Chien S, Li S, Shiu YT, Li Y , Molecular basis of mechanical modulation of endothelial cell migration. Front Biosci 2005 May 1;10():1985-2000

Shiu YT, Weiss JA, Hoying JB, Iwamoto MN, Joung IS, Quam CT, The role of mechanical stresses in angiogenesis. Crit Rev Biomed Eng 2005;33(5):431-510

Miao H, Hu YL, Shiu YT, Yuan S, Zhao Y, Kaunas R, Wang X, Jin G, Usami S, and Chien S., Effects of flow patterns on the localization and expression of VE-cadherin at vascular endothelial cell junctions: in-vivo and in-vitro investigations. Journal of Vascular Research 2005;42():77-89

Shiu YT, Li S, Marganski WA, Usami S, Schwartz MA, Wang YL, Dembo M, Chien S., Rho mediates the shear-enhancement of endothelial cell migration and traction force generation Biophysical Journal 2004 Apr;86():2558-2565

Shiu YT, McIntire LV, In vitro studies of erythrocyte-vascular endothelium interactions. Ann Biomed Eng 2003 Dec;31(11):1299-313

Shiu YT, Li S, Yuan S, Wang Y, Nguyen P, Chien S., Shear stress-induced c-fos activation is mediated by Rho in a calcium-dependent manner Biochem Biophys Res Commun. 2003 Apr;4():548-555

Shiu YT, McIntire LV, and Udden MM., Sickle erythrocytes increase prostacyclin and endothelin-1 production by cultured human vein endothelial cells under flow conditions European Journal of Haematology 2002 Mar;68(3):163-169

Li S, Bhatia S, Hu YL, Shiu YT, Li YS, Usami S, Chien S., Effects of morphological patterning on endothelial cell migration Biorheology 2001;38():101-108

Shiu YT, Udden MM, and McIntire LV, Perfusion with sickle erythrocytes upregulates ICAM-1and VCAM-1 gene expression in cultured human endothelial cells Blood 2000;95():3232-3241