Course Information for 6304 - Intro to Polymers & Biopolymers
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Primary Instructor: Michael (Seungju) Yu
Designation:Elective
Credits: 3.0
Semesters Offered:Fall
Frequency Offered:Annual
Prerequisites:Organic chemistry and Biochemistry (or closely related class), or permission from Dr. Yu
Class Schedule: T/Th 10:45-12:05
Catalog Description: This class is designed to provide comprehensive review of synthetic tools for making natural and artificial biopolymers, and, at the same time, give students creative perspective in biopolymer design. This is achieved by reviewing the similarity and difference in chemistry, molecular structures, and high-order structures between synthetic polymers and naturally derived biopolymers. The class will first review key aspects of polymer science (chemistry, physics, and morphology) which are relevant for biomedical applications. The class will then focus on synthesis of i) peptides and proteins, ii) genes, and iii) polysaccharides. Wide range of topics will be covered from classic synthesis such as solid-phase peptide synthesis, recombinant DNA technology, and sugar chemistry to more contemporary topics including living polymerization of poly(amino acids), phage display and combinatorial synthesis, unnatural amino acids, peptide nucleic acids, as well as the latest topics in chemical biology.
Course Syllabus:Syllabus_6304.pdf