Professor Douglas Christensen
Address:
DEPARTMENT OF BIOENGINEERING
UNIVERSITY OF UTAH
50 S. CENTRAL CAMPUS DR., ROOM 2480
SALT LAKE CITY, UT 84112-9202

Office: Merrill Engineering Building, Room 2456
Tel.: (801) 585-3651, Fax: (801) 585-5361
E-mail:
christen@ee.utah.edu

Education

Professional Data


Teaching Activities


Research Interests

Waves used for biological applications, including optical biosensors, ultrasonic imaging and ultrasonic energy delivery.
Current projects include:

Planar-Waveguide Fluorescence Immunosensor:

The evanescent portion of a waveguided laser beam excites fluorescence when an analyte being measured binds to antibodies immobilized on the surface of a planar waveguide. This homogeneous assay is rapid and does not require operator wash steps. Using disposable cartridges, the system is now being studied as a clinical point-of-care sensor and for biological warfare detection. The project is in collaboration with Prof. Jim Herron.

 

Ultrasonic Enhancement of Drug Delivery:

Ultrasound modifies the release and uptake of drug delivered to tissues.  Localizing the action of a drug to targeted tissues increases the effectiveness of the treatment while sparing untargeted tissue. These projects are being carried out in collaboration with Profs. Natalya Rapoport and William Pitt.

 

Modeling of Therapeutic Ultrasound:

Ultrasound can be used as an energy delivery means.  It has found use as a drug-delivery modality, in bone healing, and in tissue heating and ablation.  To model the path of the ultrasound beam in imhomogeneous tissue, we have developed a numerical technique called the fast hybrid angular spectrum method (HAS).  This project is in collaboration with Profs. Bob Roemer, Dennis Parker and Mikhail Skliar.


Books

Recent Publications

Recent Patents

Recent Conference Papers