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Research Highlights
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Research
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Decoding Neural Signals
The Greger lab is unraveling neural processing with multichannel electrical recording and stimulation to develop visual and limb prostheses.
Silken Packaging
Gene therapeutics are delivered in silk-elastinlike protein polymers developed by the Ghandehari lab.
Novel SPECT
Dr. Zeng’s research group is investigating a novel spinning slit gamma camera that provides high resolution images for small animal SPECT.
Fibronectin Fibrils
Dr. Ed Clark's research group investigates the effects of mechanical stress on actin cytoskeleton and extracellular matrix.
Genomic Signal Processing
Orly Alter discovers cellular mechanisms and predicts the outcome of cancers from mathematical modeling of DNA microarray data.
Tissue Integration
The Grainger lab characterizes and models macrophage activation in an effort to reduce the immune response to implant biomaterials
Targeted Cancer Drugs
Kopecek's research group has developed a new approach for targeted delivery of anticancer drugs.
Tissue Engineering
The Keck Center uses protein-resistant coating to promote cell responses with high degrees of bioactivity.
Magnet Resonance Tomography
Dr. Sachse and collegues use digital image processing to aid in the diagnosis of various pathologies.
Skeleton in the Scanner
Researchers at the UCAIR demonstrate micro-computed tomography images.
Honeycomb Hydrogels
Dr. Kopecek's group deals with the design and synthesis of novel hybrid hydrogel systems.
Cardiac Electrophysiology
Dr. Spitzer and collegues study cardiac cellular electrophysiology and cardiac intracellular pH regulation.
Preventing HIV
Novel microbicide-releasing polymers developed by the Kiser group aim to prevent HIV infection in third-world countries.
Mathematics of Heart Attacks
Dr. Keener investigates the dynamics of cardiac arrhythmias and the mechanisms of fibrillation.
Brain Interface
Dr. Normann and collegues investigate neuroprosthetics and vision neurophysiology.
Actin Filament Orientation
Dr. Ed Clark's research groupstudies the effects of mechanical stress on actin cytoskeleton and extracellular matrix.
Sticky Kisses of P. californica
Dr. Stewart and colleagues find bonding mechanism used by P. californica to build protective tubes.
Axon Actin Stain
Dr. Hlady's research group studies axon (green) navigation through a permissive (dark) and inhibitory (red) surface pattern.
Dosing for Organ Motion
A lung model developed at the SCI Institute by Sarong Joshi helps clinicians adjust tumor radiation dosing for breathing motion.
Planar Waveguide
A planar waveguide Drs. Christensen and Herron use in a fluorescence immunoassay instrument.
Sensor Networks
Dr. Henderson's research group is developing a network that mimics biological systems, with applications in physiological monitoring.
Anesthesiology
Dr. Westenskow uses patient simulators to test the performance enhancement provided by innovative information display designs.
Human Heart Model
Image of anatomical model of human heart constructed from Visible Female data set done by Dr. Sachse's research group.
Wound Closure
Dr. Yan-Ting Shiu and her research group investigate the development of cardiovascular complications in diabetes.
Exploded Polygonal Surface
Dr. Weiss's group uses computational techniques to investigate biomechanics and healing of tissues.
Infrared hearing?
Dr. Rabbitt's group can stimulate neurons using penetrating infrared light, potentially improving hearing or other sensory prostheses.
Tissue Engineering
Researchers at the Keck Center work to rebuild damaged tissues of the brain, spinal cord and vocal tissue.
Mapping the Brain
The Anderson group correlates sensory processing to areas of activity in the brain using sophisticated live imaging techniques.
Water on the Brain
Staining brain tissue enables Dr. Hsu to study hydrocephalus on the cellular level.
Preventing IV Infections
Catheter Connections, the Medical Accelerator program's first success, manufactures DualCap devices to keep IVs sterile.
Living Heart Cells
Dr. Spitzer and collegues use confocal microscopy to study living heart cells.
Mapping the Heart
Measurements and simulations run by the MacLeod lab at the SCI Institute show electrical activity of the heart through time and space.
Gene Delivery
Sung Wan Kim has designed innovative polymers such as these gene delivery micelles for over 35 years.
Neural Processing
With systems that interact with neural networks, the White Lab strives to learn basics of brain function.
Respiration Models
Dr. Saam's research group develops 3D biologically based fluid-dynamics models for respiration in the mammalian respiratory tract.
Hollow Fiber Membranes
Some of the Keck Center's efforts are currently focused on tissue remodeling within the CNS.
X-ray CT of the Heart
Dr. Frederic Noo's group tests X-ray CT reconstruction algorithms using analytical heart model they created.
Neural Engineering
Researchers at the Keck Center study biomaterials which may induce tissue oprganization.
Probing molecules
The Harris group uses advanced microscopy and spectroscopy techniques to analyze individual molecules and complex surfaces.
Calculus Made Easy
Dr. Rabbitt and colleagues find that hair-cell/afferent synapses perform a mathematical derivative.
Smart Biomaterials
Self-assembly and electrostatic interactions drive the gelation of polymer-protein hybrid hydrogels developed by the Kopecek group.
Anti-thrombotic coating
The Grainger lab is developing a heparin-enriching surface coating to improve biocompatibility of blood contacting materials.
Growth Cone Navigation
Dr. Hlady's research group investigates the navigation of neurons on a pattern of inhibitory signals.
Cardiac MRI
Dr. DiBella and colleagues are developing new ways to acquire and process dynamic contrast MRI data to determine regional blood flow.
Basilar Tip Aneurysm
Dr. Dennis Parker and colleagues are developing high resolution MRA protocol and a segmentation algorithm
Glial Precursors
The Keck Center investigates factors that influence orientation of Precursor-derived Astrocytes.
Ultrasonic Drug Delivery
Dr. Rapoport's research group investigates uptake of localized drugs by tumor cells, triggered by local ultrasound.
Rat Heart Model
Dr. Sachse's research group developed an electro-mechanical simulation with biventricular model of the rat heart.
Reconstruction Algorithms
Dr. Zeng’s research group is developing reconstruction algorithms for new semiconductor (CZT) nuclear medicine gamma-ray cameras.
OBOC Library Screening
Dr. Kopecek's group works on a HPMA copolymer based drug delivery system for targeted chemotherapy of lymphoma.
Real-Time Microarrays
Dr. Blair and colleagues develop technologies for the application of protein and expression arrays and rapid screenings of pathogens.
Deep Brain Stimulation
The Dorval Lab is developing safer patterns of electrical stimulation to reduce tremor caused by Parkinson’s and other diseases.
Dual-Modality PET/CT
Dr. Kadrmas is developing algorithms and methods to improve both PET lesion detectability performance and quantitative accuracy.
Heart Waves
Dr. Sachse's research group simulates an electrophysiological scroll wave in static model of heart wall.
Crawling Cancer
Dr. Holman has identified proteins that play roles in the regulation of cancer cell movement.
Drug Resistance
Dr. Rapoport's research group investigates multidrug resistant cells, which are sensitized by polymeric micelles.
Aggrecan Adhesion Map
Dr. Hlady's research group investigates the assembly of aggrecan in a network of non-adhesive mesh.
Human Foot Model
Dr. Brown's group developed a six degree-of-freedom model of the human talocrural, subtalar and talonavicular joints.
Microanalytics
Surface enhanced Raman Scattering is one of many microanalytical techniques Marc Porter's group uses for miniature and high-throughput diagnostics.
Models of Genetic Networks
Dr. Myers's group is developing methods for modeling and analyzing genetic networks using stochastic asynchronous circuits.
Intraocular Drug Delivery
An intraocular drug delivery device used by Dr. Ambati for treating macular degeneration.
Lectin Conjugates
Kopecek's research group designed, synthesized and evaluated lectin - HPMA copolymer drug conjugates.
Cell Migration
Dr. Shiu and her research group investigate the biophysical and biochemical bases of vascular cell migration.
Fibroblast Coil
Researchers at the Keck Center have developed a number of drug delivery devices.
